Everything about megatomi.com
Everything about megatomi.com
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Swiftly attain sections as skinny or thick as your software requires, with out stressing about getting rid of or distorting precious tissue samples.
Megatome is a vibrating microtome meant to part a broad number of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With significant blade vibrating frequency and minimized blade deflection, Megatome allows higher-throughput tissue sectioning with uniform surface profile, together with negligible tissue problems and information decline.
Antibodies may perhaps just take weeks to diffuse by way of only a few millimeters of tissue, which has a steep labeling gradient from floor to core.
Megatome is created for accuracy: the blade vibrates at a better frequency and bigger amplitude assortment than other microtomes, and encompasses a distinctive deflection Manage system.
SE takes advantage of a rotational electrical subject to disperse hugely electromobile molecules (including antibodies or surfactant micelles) all through a porous sample without the need of damaging electrically billed buildings in the tissue. This enables 2-4 day clearing of intact organs,
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It’s time and energy to improve your microtome to Megatome. With accurate superior-frequency slicing for an unmatched variety of sample sizes and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for varied purposes.
The SmartSPIM light-weight sheet microscope delivers unparalleled resolution and acquisition pace throughout intact tissue volumes, although its modular design and style helps you to update and personalize personal parts.
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SHIELD avoids the variability of hydrogel embedding and the knowledge decline from PFA preservation, megatomi.com protecting specimens for several rounds of processing.
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Our novel Protect tissue preservation system forms intramolecular bonds using polyfunctional, flexible epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.